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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
RicanMix (2018)

Based on 25%holandia Pharmaceuticals limited experience with top medications, 20-30% of American males aged 40 or above, with a history of cardiovascular disease or male factor, were prescribed Cialis to help lower their blood pressure. After taking the tablet, participants werecohol-raints free, and were unable to take other drugs containing alpha-blockers or other antihypertensive medications. This combination product was designed to provide added value by relaxing the blood-pressure-lowering effects of certain medications.

Cialis is used to help lower blood pressure in the following ways:

  • It helps improve blood flow to the penis, resulting in erections when sexually stimulated.
  • It can also help with pain when sitting or standing.
  • It can also help with headache and dizziness when standing.
  • Cialis can be taken with or without food.

C.

Nitrates (e.g.

This article will provide an in-depth overview of generic Cialis (Tadalafil) and why it is prescribed.

What is Generic Cialis (Tadalafil)?

Generic drugs are medicines produced under similar licence and licence from a approved brand name drug Agency for prescription medicines (AAP) and Government Drug Registering Office (DDRI).

Generic drugs are prescribed for the treatment of erectile dysfunction (ED) and other sexual problems; pulmonary arterial hypertension (PAH); pulmonary veno-occlusive disease (PODD) and other diseases associated with inflammation (neurological disorders); and high blood pressure.

Strength of generic Cialis (Tadalafil): Cialis is licenced for treating both male and female sexual problems in adult men and in juvenile female androgens (male and female sex hormones). It works by increasing blood flow to the penis to help a man get and keep an erection.

Erectile dysfunction is the inability to get or keep an erection, which is the inability to keep a hard and long erection for longer than desired. It is caused by an imbalance of blood flow to the penis due to genetic or hormonal problems. Genetic factors play a large role in ED and PANDHD.

AAP recommends AAP recommended that:

  • A man should not start taking generic Cialis until the supply of the medicine expires.
  • Generic Cialis can only be prescribed by a GP. If a man does not get a prescription by the time they get to GP’s, they will need to sign an informed consent form.
  • A person with erectile dysfunction should not take generic Cialis without first consulting a GP.

DDRI means doctor approved pharmaceutical company. It is an individual license from a approved pharmaceutical company Agency for prescription medicines (AAP).

Generic Cialis (Tadalafil) Label

The generic Cialis (Tadalafil) product label is a reference that provides the following information:

  • The drug is not to be confused with the brand name Cialis (sildenafil).
  • The drug is not available in the United States.
  • The drug is supplied in a strength of 2.5 mg, 5 mg and 10 mg tablets.

The strength and quantity of the drug are specified in the strength and quantity label. It is not possible to reliably estimate the strength and quantity of the drug as it is usually available in packs of 30 tablets. The strength and quantity of the drug are determined by the company (AAP) with which it is licensed.

The brand name of the drug are Cialis (sildenafil).

How to take Generic Cialis (Tadalafil)?

Take this medicine in the dose and duration as advised by your doctor. Swallow the tablet as a whole. Do not chew, crush or break it. Generic Cialis (Tadalafil) tablets are taken whole with a glass of water.

Side effects

The following are the most common side effects of Generic Cialis (Tadalafil):

  • Headache
  • Indigestion
  • Back pain
  • Muscle aches
  • Flushing
  • Nasal congestion
  • Dizziness
  • Insomnia
  • Fatigue
  • Increase in high blood pressure

The following are the less common but more serious side effects of Generic Cialis (Tadalafil):

  • Palpitations
  • Stomach pain
  • Rash
  • Seizures

Generic Cialis (Tadalafil) side effects are rare but may include:

  • Erectile dysfunction
  • Respiratory depression
  • Dry mouth
  • Excessive sweating
  • Allergic reactions

The above is not a complete list of side effects that may occur.

Tadalafil belongs to the group of medicines called phosphodiesterase type 5 (PDE 5) inhibitors, primarily used to treat erectile dysfunction (impotence) and benign prostatic hyperplasia (BPH). Erectile dysfunction is the inability to keep a hard and erect penis suitable for sexual activity. Benign prostatic hyperplasia, also called prostate enlargement, is the non-cancerous growth of the prostate gland.

Tadalafil contains ‘Tadalafil’, which works by relaxing the blood vessels in the penis; this allows the blood to flow into the penis when the person is sexually excited. Thereby, it helps to treat erectile dysfunction. Tadalafil relaxes the bladder and prostate muscles, thereby reducing enlarged prostate symptoms such as difficulty in urination and urgent need to urinate.

You are advised to take Tadalafil for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as headache, back pain, muscle pain, pain in the legs and arms, nasal congestion, indigestion, and facial flushing. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Tadalafil if you are taking nitrates (used to treat angina), riociguat (used to treat pulmonary hypertension) or alpha-blockers; if you have heart problems or stroke, low blood pressure or uncontrolled high blood pressure. Tadalafil is not intended for use in women. Tadalafil may cause dizziness, so drive with caution. Avoid consuming alcohol as it might cause increased dizziness. Tadalafil should not be given to children as safety and effectiveness have not been established. Keep your doctor informed about your health condition and the medicines you are taking to avoid unpleasant side effects.

akeshen brand name of Tadalafil :

Active ingredient: Tadalafil (Cialis) 2.5mg, 5mg, 10mg, and 20mg tablets.Dosage:5mg, 10mg, and 20mg. (Must be taken once a day).

busulfame potassium Tadalafil 5mg, 10mg, and 20mg

dosage. Can be taken with or without food.

Uses of Tadalafil: Tadalafil is used to treat the symptoms of erectile dysfunction (also called impotence). Symptoms include difficulty in getting or keeping an erection, difficulty in achieving it, and increased blood pressure in the penis. Before you take Tadalafil, your doctor will ask you to speak to your doctor if you have: urgent need to urinate, urgent need to have sex or if you are having problems with telephone or video sex. You must not take Tadalafil if you are taking nitrates (used to treat diabetes). alpha-blockers for high blood pressure. A medication for irregular heartbeat or muscle pain. Diabetes. Tadalafil is used to treat benign prostatic hyperplasia (BPH) or the condition of the prostate in men. BPH is the growth of the prostate gland and is the inability to keep that size and control of blood pressure needed to keep that infection in one of the walls of the enlarged prostate to function effectively. Symptoms of BPH include the pain in your legs, chest and back, and the freshness of your urine and breath. Tadalafil can help relieve these symptoms and, once you are able to achieve a erection, it will continue to do so until the infection has completely subside.

Uses of Tadalafil: Tadalafil is used to treat symptoms of erectile dysfunction (also called impotence). Symptoms include difficulty in getting or keeping an erection, increased blood pressure in the penis, and difficulty with maintaining a hard and erect penis. Doctors have stated that, since Tadalafil is only available with a doctor's prescription, it should only be taken if the doctor has judged that the treatment and the potential benefits the treatment produce would be adequate to relieve your erectile dysfunction.

Uses of Tadalafil: Tadalafil is used to treat symptoms of benign prostatic hyperplasia (BPH) in men. BPH is the growth of the prostate gland and is the inability to keep that pressure in the enlarged prostate to grow. Symptoms of benign prostatic hyperplasia include the flow of a bladder or bladder disorder, difficulty in passing urine ( urine out), and the need to pass urine for at least six hours.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

Read more about Cialis at atLearn more about. Qiao-chang is a professional pharmacist, a freelance writer, and a busy mom. After all, she’s just a mom. But she’s also a busy mom. She’s the one overseeing the grocery delivery, grocery sales, and other related services for her baby. What she doesn’t understand is, what can women do to manage their busy lifestyle?Yuehye is a freelance writer and a busy mom.